2023 – Nobel Prize Physiology or Medicine

Article Title: 2023 – Nobel Prize Physiology or Medicine

03-10-2023

Current Events Current Affairs Analysis

Winners:

Hungarian biochemist Katalin Karikó

American physician-scientist Drew Weissman

Topic:

“for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19

Other Facts:

Dr. Karikó is only the 13th woman to win the prize.

mRNA stands for messenger RNA, a type of molecule that carries instructions from the DNA to a cell’s cytoplasm, where those messages are ‘read’ to produce various proteins.

mRNA vaccine contains mRNA that has the genetic information to make harmless viral protein.

mRNA from vaccines does not enter the nucleus and does not alter DNA.

These vaccines use mRNA that directs cells to produce copies of a protein on the outside of the coronavirus known as the “spike protein”.

mRNA – needs to be kept at cold storage : -25degree Celsius

Example mRNA vaccine

Pfizer-BioNech, Moderna

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