Article Title: Sickle Cell Disease
28-02-2023
Science & Technology Prelims Plus
Why is in news? Sickle Cell Disease is a multi-sectoral mission leveraging community mobilization and stakeholder collaboration: Dr. V K Paul
SCD is a chronic single gene disorder causing a debilitating systemic syndrome characterized by chronic anaemia, acute painful episodes, organ infarction and chronic organ damage and by a significant reduction in life expectancy.
Symptoms:
Symptoms of sickle cell disease can vary, but some common symptoms include:
Chronic Anaemia: leading to fatigue, weakness, and paleness.
Painful episodes (also known as sickle cell crisis): these can cause sudden and intense pain in the bones, chest, back, arms, and legs.
Delayed growth and puberty
Treatment:
Blood Transfusions: These can help relieve anaemia and reduce the risk of pain crises.
Hydroxyurea: This is a medication that can help reduce the frequency of painful episodes and prevent some of the long-term complications of the disease.
It can also be treated by bone marrow or stem cell transplantation
Government Initiatives to Tackle SCD:
Government has released technical operational guidelines for prevention and control of hemoglobinopathies in 2016 including sickle cell anaemia.
Integrated centers have also been established in 22 tribal districts for treatment and diagnosis.
The State Haemoglobinopathy Mission has been established in Madhya Pradesh to address the challenges in screening and management of the disease.
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