Onchocerciasis (River Blindness)

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Onchocerciasis (river Blindness)

View December 2025 Crrent Affairs

Context

  • Niger has been officially declared by its government and verified by the World Health Organization (WHO) as the first African country to eliminate onchocerciasis, also known as river blindness.
  • This achievement marks a significant public health milestone in the fight against neglected tropical diseases (NTDs) in Africa.

What is Onchocerciasis?

  • Cause: Parasitic infection by the filarial worm Onchocerca volvulus.
  • Transmission: By infected Simulium blackflies, which breed near fast-flowing rivers and streams.
  • Endemic Regions: Over 99% of cases occur in sub-Saharan Africa and Yemen; small pockets exist in Brazil–Venezuela border.
  • Significance: Second leading infectious cause of blindness, after trachoma.

Defeating River Blindness - USF Magazine Summer 2013

Key Features

1Pathology

oChronic infection with microfilariae causes intense inflammation.

oLeads to severe itching, disfiguring skin changes (“leopard skin”), and progressive eye damage.

oAdult worms live 10–15 years, necessitating long-term treatment.

2Symptoms

oSkin: Itching, rashes, thickening, depigmentation

oEyes: Lesions, impaired vision, potential permanent blindness

oNodules: Firm subcutaneous lumps containing adult worms

oChildren: Early infection linked to epilepsy in some regions

3Community Impact

oBlindness and disfigurement reduce productivity, increase poverty risk, and affect quality of life.

Treatment

  • Ivermectin (Mectizan):
  • Administered once or twice yearly for 10–15 years to interrupt transmission.
  • Mass drug administration and vector control programs are crucial for elimination.

Significance of Niger’s Achievement

  • Public Health Milestone: First African country to eliminate river blindness.
  • Global NTD Goals: Supports WHO’s neglected tropical disease roadmap.
  • Model for Other Endemic Countries: Demonstrates effectiveness of mass drug administration, community engagement, and surveillance.
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